Summary of laboratory evaluations
| Evaluations | Results | Reference values |
| General toxic and metabolic studies | ||
| AST, U/L | 67 | 5–34 |
| ALT, U/L | 93 | 6–55 |
| TSH, µIU/mL | 0.153 | 0.350–4.940 |
| CK, U/L | 1200 | 29–200 |
| Aldolase, U/L | 15.8 | <8.1 |
| Serological infectious studies | ||
| Leucocytes, ×109/L | 18.5 | 3.5–10.5 |
| Neutrophils, ×109/L | 15.5 | 1.78–5.38 |
| Lactic acid, mmol/L | 0.67 | 0.5–2.2 |
| Procalcitonin, ng/mL | 0.35 | <0.05 |
| RPR | Non-reactive | Non-reactive |
| HIV-1 | Non-reactive | Non-reactive |
| Cryptococcal antigen | Negative | Negative |
| Lyme disease IgG/IgM | Negative | Negative |
| Rickettsia IgG/IgM | Negative | Negative |
| Typhus IgG/IgM | Negative | Negative |
| Nasopharyngeal swab infectious studies | ||
| Human metapneumovirus, parainfluenza virus 1–4, rhinovirus, SARS-CoV-2, influenza A, influenza B, RSV, adenovirus, Bordetella pertussis, Chlamydophila pneumoniae, Mycoplasma pneumoniae, coronavirus 229E, coronavirus HKU1, coronavirus NL63, coronavirus OC43 | Not detected | Not detected |
| Immunology studies | ||
| Rheumatoid factor | Positive (1:2) | Negative |
| ANA | Positive (1:160) | Negative |
| Anti-dsDNA, RNP, Smith, Ro, La | Negative | Negative |
| Anti Jo-1 IgG | Negative | Negative |
| ANCA (Pr3, MPO) | Negative | Negative |
| Anticardiolipin IgG, IgM | Negative | Negative |
| C3 complement, mg/dL | 108 | 82–193 |
| C4 complement, mg/dL | 41 | 15–57 |
| CRP, mg/dL | 139 | 0.00–0.50 |
| Ferritin, ng/mL | 396.70 | 5–275 |
| CSF studies | ||
| White cell count (5% neutrophils, 77% lymphocytes, 18% monocytes), /×106/L | 120 | ≤5 |
| RBC, /106/L | 0 | 0–5 |
| Glucose, mg/dL | 65 | 40–70 |
| Protein, mg/dL | 124 | 15–45 |
| IgG index (CSF+blood) | Increased | Normal |
| Immunofixation electrophoresis | Normal | Normal |
| Culture/Gram stain | No organisms seen | No organisms seen |
| AFB culture+smear | No acid-fast bacilli seen | No acid-fast bacilli seen |
| Fungus | No fungi seen | No fungi seen |
| India ink | No encapsulated yeast seen | No encapsulated yeast seen |
| VDRL | Non-reactive | Non-reactive |
| Meningoencephalitis panel | ||
| CMV, Escherichia coli K1, Haemophilus influenzae, herpes simplex virus 1, 2 and 6, human parechovirus, Listeria monocytogenes, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pneumoniae, Enterovirus, varicella-zoster virus, Cryptococcus neoformans/gattii, West Nile virus | Not detected | Not detected |
| Autoimmune encephalitis panel | ||
| ANNA 1 (Hu), ANNA 2 (Ri), ANNA 3, PCA1 (Yo), PCA2, PCA-Tr (DNER), AGNA/SOX1, amphiphysin, CRMP5/CV2, GAD65, Ma2/Ta, Myelin Ab, aquaporin 4, NMDAR1, AMPAR1, AMPAR2, GABABR, LGI1, CASPR2, DPPX Rec, VGKC | Negative | Negative |
Ab, antibody; AFB, acid-fast bacillus ; AGNA, antiglial nuclear antibody; ALT, alanine aminotransferase; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; ANA, antinuclear antibodies; ANCA, antineutrophil cytoplasmic antibodies ; ANNA 1, type 1 antineuronal nuclear antibody; ANNA 2, type 2 antineuronal nuclear antibody; ANNA 3, type 3 antineuronal nuclear antibody; AST, aspartate aminotransferase; CASPR2, contactin-associated protein-2; CK, creatine kinase; CMV, cytomegalovirus; CRMP5, collapsin response mediator protein-5; CRP, C-reactive protein; CSF, cerebrospinal fluid; DNER, Delta/Notch-like epidermal growth factor-related receptor; DPPX Rec, dipeptidyl-peptidase–like protein 6 receptor; dsDNA, double-stranded DNA; GABABR, γ-aminobutyric acid-B receptor; GAD, glutamic acid decarboxylase; HIV-1, human immunodeficiency virus type 1; LGI1, Leucine-rich glioma-inactivated protein 1; MPO, myeloperoxidase; NMDAR1, N-methyl-d-aspartate receptor-1; PCA, Purkinje cytoplasmic antibody ; Pr3, proteinase 3; RBC, red blood cells; RNP, ribonucleoprotein; RPR, rapid plasma reagin; RSV, respiratory syncytial virus; RT-PCR, real-time PCR; TSH, thyroid stimulating hormone; VDRL, venereal disease research laboratory test; VGKC, voltage-gated potassium channel.