Table 2

Results for the 65-year-old male patient

Beginning of June 2020End of June 2020
Itraconazole dose100 mg two times per week100 mg/day
Blood pressure/mm Hg140/85Not registered
K+/mmol/L (3.5–4.4)4.24.3
Na+/mmol/L (137–144)141140
Aldosterone/pmol/L (102–1197)658178
Renin/mIU/L (5.3–99.1)6515
ARR (<31)10.111.9
Urinary cortisol-metabolites/mg/day (4.0–13 mg/day)7.43.7
Urinary cortisol-to-cortisone ratio (measured as THF +allo-THF/THE*)(0.59+1.7)/3.6=0.81(0.39+0.99)/1=1.38
  • *The ratio of the principal metabolites of cortisol (tetrahydrocortisol=THF and allo-tetrahydrocortisol=allo THF) to the principal metabolite of cortisone (tetrahydrocortisone=THE)

  • ARR, aldosterone renin ratio.