Brief timeline of clinical course during previous and our hospital
| Events | Time (hours) | Heart rate (/min) | RR (/min) | Blood pressure (mmHg) | SpO2 (%) | Additional notes |
| Before intubation | 12:30 | 72 | 16 | 160/100 | 99 | Obese male in his 40s admitted to the previous hospital for neck operation. |
| After extubation | 17:00 | 130 | 40 | 200/120 | 23 | Developed respiratory distress after extubation. Reintubation was performed. |
| Departure from previous hospital | 19:43 | 70 | 25 | 110/70 | 70 | Transferred to our hospital for further treatment. |
| Hospital arrival | 20:08 | 120 | 40 | 231/160 | 54 | Pink, frothy fluid came out of the endotracheal tube and the patient was agitated. |
| Decision to introduce ECMO | 20:20 | 42 | 25 | 127/90 | 82 | Gradually became bradycardia. Approached death due to hypoxia and hypercarbia. |
| ECMO initiation | 20:26 | 76 | 12 | 112/88 | 98 | Improved rapidly with initiation of ECMO. |
| ICU admission | 22:50 | 59 | 12 | 123/68 | 100 | Diagnosis of NPPE was made. Became stable with ECMO. |
| Weaned from ECMO | 13:12 | 63 | 16 | 122/70 | 100 | Weaned from ECMO. Respiratory settings: PC–AC mode, FiO2 45%, PEEP 20 cmH2O, PIP 30 cmH2O, RR 15/min. PaO2/FiO2 ratio >200. |
ECMO, extracorporeal membrane oxygenation; NPPE, negative pressure pulmonary oedema; PC–AC, pressure-control and assist-control; PEEP, positive end-expiratory pressure; PIP, peak inspiratory pressure; RR, respiratory ratio.