Next generation cancer gene panel
| Genes for which entire coding panel is interrogated | |||||||||||
| ABL1 | ABL2 | ACVR1B | AKAP9 | AKT1 | AKT2 | AKT3 | ALK | AMER1 | APC | AR | ARAF |
| ARFRP1 | ARID1A | ARID1B | ARID2 | ASPSCR1 | ASXL1 | ATF6 | ATM | ATP1A1 | ATP2B3 | ATR | ATRX |
| AURKA | AURKB | AXIN1 | AXL | BAP1 | BARD1 | BCL11A | BCL11B | BCL2 | BCL2L1 | BCL2L2 | BCL6 |
| BCOR | BCORL1 | BLM | BMPR1A | BRAF | BRCA1 | BRCA2 | BRD4 | BRIP1 | BTG1 | BTK | C11orf30 |
| CACNA1D | CAMTA1 | CARD11 | CASP8 | CBFB | CBL | CBLB | CCND1 | CCND2 | CCND3 | CCNE1 | CD274 |
| CD79A | CD79B | CDC73 | CDH1 | CDH11 | CDK12 | CDK4 | CDK6 | CDK8 | CDKN1A | CDKN1B | CDKN2A |
| CDKN2B | CDKN2C | CEBPA | CHD2 | CHD4 | CHEK1 | CHEK2 | CIC | CLTCL1 | COL1A1 | CREBBP | CRKL |
| CRLF2 | CSF1R | CSF3R | CTCF | CTNNA1 | CTNNB1 | CUL3 | CYLD | DAXX | DDIT3 | DDR2 | DICER1 |
| DNM2 | DNMT3A | DOT1L | EBF1 | EGFR | EIF1AX | EP300 | EPHA3 | EPHA5 | EPHA7 | EPHB1 | ERBB2 |
| ERBB3 | ERBB4 | ERCC3 | ERCC4 | ERCC5 | ERG | ERRFI1 | ESR1 | ETV1 | ETV4 | ETV5 | ETV6 |
| EWSR1 | EXT1 | EZH2 | FAM46C | FANCA | FANCC | FANCD2 | FANCE | FANCF | FANCG | FANCL | FAS |
| FAT1 | FBXO11 | FBXW7 | FGF10 | FGF14 | FGF19 | FGF23 | FGF3 | FGF4 | FGF6 | FGFR1 | FGFR2 |
| FGFR3 | FGFR4 | FH | FLCN | FLT1 | FLT3 | FLT4 | FOXA1 | FOXL2 | FOXO1 | FOXP1 | FRS2 |
| FUBP1 | FUS | GABRA6 | GATA1 | GATA2 | GATA3 | GATA4 | GATA6 | GID4 | GLI1 | GMPS | GNA11 |
| GNA13 | GNAQ | GNAS | GPR124 | GRIN2A | GRM3 | GSK3B | H3F3A | HGF | HIP1 | HNF1A | HRAS |
| HSD3B1 | HSP90AA1 | IDH1 | IDH2 | IGF1R | IGF2 | IKBKE | IKZF1 | IL7R | INHBA | INPP4B | IRF2 |
| IRF4 | IRS2 | ITK | JAK1 | JAK2 | JAK3 | JUN | KAT6A | KAT6B | KDM5A | KDM5C | KDM6A |
| KDR | KEAP1 | KEL | KIF5B | KIT | KLHL6 | KMT2A | KMT2D | KRAS | LCP1 | LIFR | LMO1 |
| LRIG3 | LRP1B | LYN | LZTR1 | MAGI2 | MAML2 | MAP2K1 | MAP2K2 | MAP2K4 | MAP3K1 | MCL1 | MDM2 |
| MDM4 | MED12 | MEF2B | MEN1 | MET | MITF | MLH1 | MLLT3 | MLLT4 | MN1 | MPL | MRE11A |
| MSH2 | MSH6 | MTOR | MUTYH | MYB | MYC | MYCL | MYCN | MYD88 | MYH11 | MYH9 | NCOA1 |
| NCOA2 | NF1 | NF2 | NFE2L2 | NFKBIA | NIN | NKX2-1 | NOTCH1 | NOTCH2 | NOTCH3 | NPM1 | NR4A3 |
| NRAS | NSD1 | NTRK1 | NTRK2 | NTRK3 | NUMA1 | NUP214 | NUP93 | NUP98 | PAK3 | PALB2 | PARK2 |
| PAX3 | PAX5 | PAX7 | PBRM1 | PCM1 | PDCD1LG2 | PDGFRA | PDGFRB | PDK1 | PIK3C2B | PIK3CA | PIK3CB |
| PIK3CG | PIK3R1 | PIK3R2 | PLCG2 | PMS1 | PMS2 | POLD1 | POLE | PPARG | PPP2R1A | PRDM1 | PRDM16 |
| PREX2 | PRKAR1A | PRKCI | PRKDC | PRSS8 | PTCH1 | PTEN | PTPN11 | PTPRC | QKI | RAC1 | RAD21 |
| RAD50 | RAD51 | RAF1 | RALGDS | RANBP17 | RANBP2 | RARA | RB1 | RBM10 | RET | RICTOR | RNF43 |
| ROS1 | RPTOR | RUNX1 | RUNX1T1 | SDHA | SDHB | SDHC | SDHD | SETBP1 | SETD2 | SF3B1 | SLC34A2 |
| SLIT2 | SMAD2 | SMAD3 | SMAD4 | SMARCA4 | SMARCB1 | SMO | SNCAIP | SOCS1 | SOX10 | SOX2 | SOX9 |
| SPEN | SPOP | SPTA1 | SRC | SRGAP3 | SS18 | STAG2 | STAT3 | STAT4 | STAT5B | STK11 | SUFU |
| SYK | TAF1 | TBX3 | TCF7L2 | TERC | TERT | TET2 | TGFBR2 | THRAP3 | TMPRSS2 | TNFAIP3 | TNFRSF14 |
| TOP1 | TOP2A | TP53 | TPR | TRIM24 | TRIM33 | TRIP11 | TRRAP | TSC1 | TSC2 | TSHR | U2AF1 |
| VEGFA | VHL | WHSC1 | WISP3 | WRN | WT1 | XPO1 | ZBTB2 | ZMYM2 | ZNF217 | ZNF384 | ZNF521 |
| Subset of genes (28) for which potential rearrangements are evaluated | |||||||||||
| ALK | ASPSCR1 | BRAF | BRD4 | DDIT3 | EGFR | ETV1 | ETV4 | ETV5 | ETV6 | EWSR1 | FGFR1 |
| FGFR2 | FGFR3 | FOXO1 | FUS | MYB | NOTCH2 | NR4A3 | NTRK1 | NTRK2 | PDGFRA | PPARG | RAF1 |
| RET | ROS1 | SS18 | TMPRSS2 | ||||||||