List of case reports on patients with signet-ring cell carcinoma of unknown primary
| Author (year) | Age (years), gender | Chief complaints | Immunohistochemistry | Therapy | Survival |
| Gregoire et al (2014)8 | 66, female | Abdominal pain | Positive for ER and PR receptors | ECF, tamoxifen and letrozole | 24 months |
| 70, female | Dyspnoea | Positive for ER and PR receptors, CK-7 | Tamoxifen, letrozole and fulvestrant | 15 months | |
| Unknown, female | Abdominal pain | Positive for ER and PR receptors; CK-7 | Tamoxifen and letrozole | 37 months | |
| Al-Taee et al (2018)10 | 73, male | Nausea, vomiting and abdominal pain | Positive for CK-7, CK-20, and E-cadherin | None | Unknown |
| O’Kane et al (2018)9 | 70, male | Incidental finding on imaging after motor vehicle accident | Positive for CK-7 and CK-20 | None | 3 months |
| Kusakari et al (2007)33 | 46, male | Incidental mass on chest imaging | Positive for CK-7 | Cisplatin, irinotecan, and S-1 | 24 months |
| Heidemann et al (2002)34 | 71, female | Sanguineous discharge after defecation | Positive for pancytokeratin and EMA | 5-Fluorouracil and folinic acid | 36 months |
| Shin et al (2011)35 | 80, male | Back pain and jaundice, MAHA | Positive for CK-20 | None | 3 weeks |
| Lara et al (2016)36 | 34, female | Severe and progressive fatigue, MAHA | Positive for ER and PR receptors | None | Unknown |
| Handa et al (2018)37 | 63, female | Incidental finding after thyroidectomy, biopsy of regional lymph node showed SRCC | Positive for PAS, CK AE1/AE3 | Palliative radiotherapy, cisplatin and S-1 | 42 months |
| Danzinger et al (2019)38 | 37, female | Dyspnoea, jaundice and epigastric pain; pregnant at 21 weeks and 5 days age of gestation | Positive for CK-7; negative for CK-20, CDX2, ER, PR, PAX8 and HER2 | Pembrolizumab | 14 days |
CDX2, caudal-type homeobox transcription factor 2; CK-7, cytokeratin-7; CK-20, cytokeratin-20; CK AE1/AE3, cytokeratin AE1/AE3; ECF, epirubicin, cisplatin, 5-fluorouracil; EMA, epithelial membrane antigen20–24; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; MAHA, microangiopathic haemolytic anaemia; PAS, periodic acid–Schiff; PAX8, paired-box gene 8; PR, progesterone receptor; SRCC, signet-ring cell carcinoma.