Table 1

Reported cases of preseptal and postseptal gonococcal cellulitis, with only one postseptal case in paediatric age

AuthorAge (years)Clinical manifestationTreatment optionsOutcome
Pereira-Ospina et al 4 2Periorbital swelling and purulent discharge from the right eye.Ceftriaxone 100 mg/kg/day intravenous for 10 days; 
Ampicillin-sulbactam 50 mg/kg/day (after discharge).
Complete resolution
Yao and Wang5 22Painful left eye with periorbital swelling and purulent discharge; feverCeftriaxone 1 g/day intravenous with oral clarithromycin 500 mg/day (empirical treatment of possible Chlamydia coinfection), for 7 days.Complete resolution
Annan and Boag3 39Purulent discharge from the left eye, conjunctival injection and periorbital oedema.Ceftriaxone 1 g/day intramuscular,  for 10 days;
Oral doxycycline (empirical treatment of possible  Chlamydia   coinfection) for 1 week.
Residual corneal scarring
Hegde et al 6 19Red and painful left eye with purulent discharge.Ceftriaxone 2000mg/day intravenous for 10 days.Increase in corneal thickness
Raja and Singh 1 42Periorbital swelling, purulent discharge, orbital pain, tenderness and erythema of both eyes.Cefuroxime and gentamicin for 48 hours
Oral cefuroxime for 1 week and topical cefuroxime and gentamicin
Complete resolution
Henderson et al 7 31Periorbital erythema, swelling, conjunctival injection, chemosis and purulent discharge of the right eye.Flucloxacillin, ampicillin and intravenous metronidazole 5 day followed by oral therapy for 7 daysComplete resolution
Frazier et al 2 15Right periorbital oedema, purulent discharge, orbital pain and tenderness, fever.Penicillin G potassium intravenous , 7 daysComplete resolution