Table 1

Hydralazine induced antinuclear cytoplasmic antibody vasculitis-patients with the pulmonary–renal syndrome, treatment and outcomes.

Author with referenceNumber of patientsPositive
MPO antibodies
Pulmonary and renal involvementTreatmentOutcome
Almroth et al201712 of 14 tested4S 4/4
Cy 2/4
Az 1/4,
P 1/4
Three out of four
died
Short and Lockwood2310102S 2/2
Cy 1/2
Not reported
Choi et al710105S 5/5
Cy 5/5
One out of four died
Yokogawa and Vivino8221S 1/1
Cy 1/1
Died
Kalra et al24111S 1/1
Cy 1/1
Died
Babar et al19211S1/1
Cy 1/1
Died
Marina et al17111S 1/1
Cy 1/1
Died
Agarwal et al25111S 1/1
Cy 1/1
Survived
Namas et al26111S 1/1
Cy 1/1
P 1/1
Survived
Rasla et al27111S1/1
Cy 1/1
P 1/1
Survived
Kumar et al91212 of 126S 5/6
Cy 5/6
MM 3/6
Five out of six survived.
  • Az, azathioprine; Cy, cyclophosphamide; MM, mycophenolate mofetil; P, plasmapheresis; S, steroids.