PT  - JOURNAL ARTICLE
AU  - Caseiro Alves, M Eduarda
AU  - Carmo, Filipa
AU  - Malato, Madalena
AU  - Cunha, Florbela
TI  - Immune thrombocytopenia in the setting of acute SARS-CoV-2 infection
AID  - 10.1136/bcr-2022-254352
DP  - 2023 Jun 01
TA  - BMJ Case Reports
PG  - e254352
VI  - 16
IP  - 6
4099  - http://casereports.bmj.com/content/16/6/e254352.short
4100  - http://casereports.bmj.com/content/16/6/e254352.full
SO  - BMJ Case Reports2023 Jun 01; 16
AB  - Immune thrombocytopenia (ITP) is an immune-mediated event, characterised by the destruction of platelets by autoantibodies resulting in isolated thrombocytopaenia (platelets <100 x109/L). In children, most cases are preceded by a viral infection. Cases of ITP in the setting of SARS-CoV-2 infection have been described. We describe a previously healthy boy, who presented with an extensive frontal and periorbital haematoma, petechial rash on the trunk and coryza. He had suffered a minor head trauma, 9 days before admission. Blood tests revealed a platelet count of 8000/µL. The remainder study was unremarkable, except for a positive SARS-CoV-2 PCR. Treatment comprised a single dose of intravenous immunoglobulin, with increase in platelet count and no recurrence. We made a working diagnosis of an ITP concurrent with a SARS-CoV-2 infection. Although few cases have been described, SARS-CoV-2 might be considered as a trigger for ITP.