PT - JOURNAL ARTICLE AU - Maria Teresa Dawid de Vera AU - Juan Daniel Prieto Cuadra AU - Dolores Domínguez Pinos AU - Isabel Hierro Martín TI - Pleural empyema secondary to perforated diverticulosis due to biliary neoplasia infiltration AID - 10.1136/bcr-2022-250061 DP - 2023 Mar 01 TA - BMJ Case Reports PG - e250061 VI - 16 IP - 3 4099 - http://casereports.bmj.com/content/16/3/e250061.short 4100 - http://casereports.bmj.com/content/16/3/e250061.full SO - BMJ Case Reports2023 Mar 01; 16 AB - A long-term female smoker presented to the emergency department with cough, greenish mucus and dyspnoea, without fever. The patient also reported abdominal pain and significant weight loss in recent months. Laboratory tests showed leucocytosis with neutrophilia, lactic acidosis and a faint left lower lobe consolidation on chest X-ray, for which she was admitted to the pneumology department and started on broad-spectrum antibiotherapy. After 3 days of clinical stability, the patient deteriorated rapidly, with worsening of analytical parameters and coma. The patient died a few hours later. Given the rapid and unexplained evolution of the disease, a clinical autopsy was requested, which revealed a left pleural empyema caused by perforated diverticula by neoplastic infiltration of biliary origin.