TY - JOUR T1 - Antiglutamate acid decarboxylase seropositive brain stem encephalitis JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2022-254026 VL - 16 IS - 3 SP - e254026 AU - Faye AlAbdulghafoor AU - Raed Behbehani AU - Abbas Johar AU - Raed Alroughani Y1 - 2023/03/01 UR - http://casereports.bmj.com/content/16/3/e254026.abstract N2 - This is a case of a previously healthy female in her fourties presenting with a subacute presentation of bilateral horizontal gaze restriction, with bilateral lower motor facial palsy. The patient’s daughter has type 1 diabetes. On investigation, the patient’s MRI revealed a lesion in the dorsal medial pons. Cerebrospinal fluid analysis revealed albuminocytological dissociation, with a negative autoimmune panel. The patient was treated with intravenous immunoglobulin, and methylprednisolone for a total of 5 days and showed mild improvement. The patient had raised serum antiglutamic acid decarboxylase (anti-GAD) levels, and the final diagnosis of GAD seropositive brain stem encephalitis was made. ER -