RT Journal Article
SR Electronic
T1 Antiglutamate acid decarboxylase seropositive brain stem encephalitis
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e254026
DO 10.1136/bcr-2022-254026
VO 16
IS 3
A1 Faye AlAbdulghafoor
A1 Raed Behbehani
A1 Abbas Johar
A1 Raed Alroughani
YR 2023
UL http://casereports.bmj.com/content/16/3/e254026.abstract
AB This is a case of a previously healthy female in her fourties presenting with a subacute presentation of bilateral horizontal gaze restriction, with bilateral lower motor facial palsy. The patient’s daughter has type 1 diabetes. On investigation, the patient’s MRI revealed a lesion in the dorsal medial pons. Cerebrospinal fluid analysis revealed albuminocytological dissociation, with a negative autoimmune panel. The patient was treated with intravenous immunoglobulin, and methylprednisolone for a total of 5 days and showed mild improvement. The patient had raised serum antiglutamic acid decarboxylase (anti-GAD) levels, and the final diagnosis of GAD seropositive brain stem encephalitis was made.