PT  - JOURNAL ARTICLE
AU  - Faye AlAbdulghafoor
AU  - Raed Behbehani
AU  - Abbas Johar
AU  - Raed Alroughani
TI  - Antiglutamate acid decarboxylase seropositive brain stem encephalitis
AID  - 10.1136/bcr-2022-254026
DP  - 2023 Mar 01
TA  - BMJ Case Reports
PG  - e254026
VI  - 16
IP  - 3
4099  - http://casereports.bmj.com/content/16/3/e254026.short
4100  - http://casereports.bmj.com/content/16/3/e254026.full
SO  - BMJ Case Reports2023 Mar 01; 16
AB  - This is a case of a previously healthy female in her fourties presenting with a subacute presentation of bilateral horizontal gaze restriction, with bilateral lower motor facial palsy. The patient’s daughter has type 1 diabetes. On investigation, the patient’s MRI revealed a lesion in the dorsal medial pons. Cerebrospinal fluid analysis revealed albuminocytological dissociation, with a negative autoimmune panel. The patient was treated with intravenous immunoglobulin, and methylprednisolone for a total of 5 days and showed mild improvement. The patient had raised serum antiglutamic acid decarboxylase (anti-GAD) levels, and the final diagnosis of GAD seropositive brain stem encephalitis was made.