PT  - JOURNAL ARTICLE
AU  - Chanyang Lee
AU  - Nathalie Falkner
AU  - Roshanak Kamyab
AU  - Ran Li
TI  - Primary angiosarcoma of the breast in an early adolescent female
AID  - 10.1136/bcr-2022-254283
DP  - 2023 Mar 01
TA  - BMJ Case Reports
PG  - e254283
VI  - 16
IP  - 3
4099  - http://casereports.bmj.com/content/16/3/e254283.short
4100  - http://casereports.bmj.com/content/16/3/e254283.full
SO  - BMJ Case Reports2023 Mar 01; 16
AB  - Primary angiosarcoma of the breast is a rare and aggressive malignancy, which arises from endothelial cells lining blood vessels. It represents less than 0.05% of all breast cancers, and more commonly affects relatively younger individuals. Reaching the correct diagnosis may be delayed, because imaging is not typical of other breast malignancies and can mimic benign processes. Clinical presentation is variable, ranging from diffuse breast oedema to a palpable discrete mass. An early adolescent female presented to her general practitioner with a palpable breast lump on self-examination. The diagnosis of primary breast angiosarcoma was confirmed on biopsy. She underwent a complete surgical resection and adjuvant chemotherapy. She remains in remission after 3 years and is undergoing regular surveillance. Due to the rarity of this condition, there is no established clinical management protocol for this condition currently. Early detection, aggressive treatment and ongoing surveillance provide the best chance of prolonged disease-free survival.