PT - JOURNAL ARTICLE AU - Abdullah, Hafez Mohammad Ammar AU - Hassan, Masroor AU - Khan, Uzma Ikhtiar AU - Ellithi, Moataz TI - Primary small cell neuroendocrine cancer of adrenal gland: a rare extrapulmonary small cell cancer AID - 10.1136/bcr-2022-250828 DP - 2023 Feb 01 TA - BMJ Case Reports PG - e250828 VI - 16 IP - 2 4099 - http://casereports.bmj.com/content/16/2/e250828.short 4100 - http://casereports.bmj.com/content/16/2/e250828.full SO - BMJ Case Reports2023 Feb 01; 16 AB - Small cell cancer is an aggressive neoplasm of neuroendocrine origin that is most commonly found in the lungs. However, up to 5% of cases can be extrapulmonary. These have been reported to be located in the gastrointestinal and genitourinary systems and rarely in other locations. Only five prior cases of small cell cancer have been reported where the primary lesion is at the adrenal gland. Here we present the case of a female patient in her mid-50s who presented with right upper quadrant pain and was diagnosed with metastatic small cell carcinoma of the adrenal gland. The patient received palliative chemotherapy for her metastatic cancer and was ultimately admitted to hospice after progression of her disease. This case and the accompanying literature review highlight a rare manifestation of extrapulmonary small cell cancer.