RT Journal Article SR Electronic T1 Successful outcome in a compound heterozygote haemoglobin E/beta-thalassaemia in pregnancy JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e252829 DO 10.1136/bcr-2022-252829 VO 16 IS 2 A1 Kalika Dubey A1 Charu Sharma A1 Suma Shet A1 Shashank Shekhar YR 2023 UL http://casereports.bmj.com/content/16/2/e252829.abstract AB Haemoglobin E (HbE) affects at least 1 million people around the world. The carrier frequency of HbE/beta-thalassaemia (HbE/β-thalassaemia) is highest in Southeast Asia. In India, the highest frequency is observed in the northeast region. Distinguishing between homozygous HbE disease and HbE/β-thalassaemia is a challenge to the haematopathologist as well as to the treating obstetrician because both are clinically and haematologically similar, posing a difficulty in managing anaemia and assessing the fetal risk for the same disease. This article reports a case of compound heterozygote HbE/β-thalassaemia in pregnancy and its successful outcome.