RT Journal Article SR Electronic T1 Splenic abscess caused by Cutibacterium acnes in a patient with multiple tooth extractions JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e250486 DO 10.1136/bcr-2022-250486 VO 16 IS 1 A1 Madalyn Walsh A1 Nicholas Wasko A1 Andrew Joseph Simms A1 Jacob Hodges YR 2023 UL http://casereports.bmj.com/content/16/1/e250486.abstract AB A woman in her 40s with a history of dental abscess presenting with a 3-month history of nightly fevers, malaise, fatigue and acutely worsening left flank pain was found to have a splenic abscess replacing almost the entire splenic parenchyma on abdominal CT. Abscess aspirate showed Gram-positive rods, and both aerobic and anaerobic cultures grew Cutibacterium acnes (previously Propionibacterium acnes), a common member of the skin microbiome. Prior case reports of C. acnes splenic abscess all involved parental inoculation via needle use. However, in the context of no percutaneous needle exposure and multiple tooth extractions immediately preceding her symptoms, the most likely source of her infection is oral flora with haematogenous or lymphatic spread to the spleen.