PT  - JOURNAL ARTICLE
AU  - Kyra Ji-Young Lee
AU  - Jue Li Seah
AU  - Sandra O’Toole
AU  - Sanjay Warrier
TI  - Xanthogranulomatous inflammation and spindle cell proliferation in response to silicone breast implant leakage
AID  - 10.1136/bcr-2022-252091
DP  - 2023 Jan 01
TA  - BMJ Case Reports
PG  - e252091
VI  - 16
IP  - 1
4099  - http://casereports.bmj.com/content/16/1/e252091.short
4100  - http://casereports.bmj.com/content/16/1/e252091.full
SO  - BMJ Case Reports2023 Jan 01; 16
AB  - This case study highlights the rare complications of silicone breast implants, as well as the diagnostic limitations of imaging. The patient initially presented with leakage of bilateral breast implants as discovered by a positron emission tomography (PET)-computerized tomography (CT) scan performed as part of a workup for small bowel Langerhans cell sarcoma metastases. The imaging results of the PET-CT scan revealed increased activity bilaterally with an enhancing, irregular, heterogeneously enhancing mass in the right breast. Given the clinical suspicion for breast implant-associated anaplastic large cell lymphoma, further investigation including surgical excision was undertaken. What initially was a concern for a serious complication of long-standing breast implants, fortuitously turned out to be a benign but exuberant xanthogranulomatous inflammatory reactive process. We hope that our report will add to the literature of this rare phenomenon and highlight it as a differential diagnosis of a mass in association with breast implants.