RT Journal Article SR Electronic T1 SMART syndrome: two cases highlighting a complex and rare complication of brain irradiation JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e249599 DO 10.1136/bcr-2022-249599 VO 15 IS 9 A1 Hanne Blakstad A1 Christine Wohlleben A1 Cathrine Saxhaug A1 Petter Brandal YR 2022 UL http://casereports.bmj.com/content/15/9/e249599.abstract AB Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare complication of radiotherapy with complex neurological impairment. Patients present with neurological symptoms and signs such as migraine, hemianopsia, hemiplegia, aphasia and/or seizures—without recurrence of neoplastic disease. In this report, we describe SMART syndrome in two adult patients 4 and 14 years following brain irradiation, respectively.