RT Journal Article SR Electronic T1 Severe bullous pemphigoid with excoriation disorder JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e250285 DO 10.1136/bcr-2022-250285 VO 15 IS 9 A1 McGowan, Kaitlin A1 Poos, Stephen A1 Vo, Nguyen YR 2022 UL http://casereports.bmj.com/content/15/9/e250285.abstract AB Bullous pemphigoid is the most common autoimmune blistering skin disease. Pathogenesis involves autoantibodies that attack the basement membrane, resulting in blisters and intense pruritus. We present a case of bullous pemphigoid with concurrent excoriation disorder in a woman in her 50s. The suspected diagnosis of bullous pemphigoid was confirmed through direct immunofluorescence testing on a specimen obtained via punch biopsy, then treated with vancomycin and steroids. In addition, cross tapering from duloxetine to fluoxetine was used to treat the patient’s excoriation disorder. The concurrent dermatological and psychiatric components, as well as the severity, made this case unique.