RT Journal Article
SR Electronic
T1 Reactivation of adult-onset Still’s disease after use of the COVID-19 ChAdOx1-S vaccine
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e249290
DO 10.1136/bcr-2022-249290
VO 15
IS 8
A1 Sebastián E Ibáñez Vodnizza
A1 Luis Morales Murillo
A1 Matías de la Rivera Vergara
A1 Roberto Saldías Martínez
YR 2022
UL http://casereports.bmj.com/content/15/8/e249290.abstract
AB A woman in her 60s with a history of adult-onset Still’s disease (AOSD) in remission for 14 years received the ChAdOx1-S vaccine as a booster to her initial vaccination schedule (two doses of CoronaVac vaccine 6 months apart). Two weeks later, she consulted for symptoms suggestive of AOSD reactivation. This was confirmed during hospitalisation, where renal and cardiac involvement were also observed. Despite using high-dose corticosteroids, troponin T and N-terminal pro hormone B-type natriuretic peptide (NT-proBNP) were persistently elevated. Tocilizumab was used, with which the patient achieved complete remission of her symptoms and normalised her laboratory tests.