PT  - JOURNAL ARTICLE
AU  - Sebastián E Ibáñez Vodnizza
AU  - Luis Morales Murillo
AU  - Matías de la Rivera Vergara
AU  - Roberto Saldías Martínez
TI  - Reactivation of adult-onset Still’s disease after use of the COVID-19 ChAdOx1-S vaccine
AID  - 10.1136/bcr-2022-249290
DP  - 2022 Aug 01
TA  - BMJ Case Reports
PG  - e249290
VI  - 15
IP  - 8
4099  - http://casereports.bmj.com/content/15/8/e249290.short
4100  - http://casereports.bmj.com/content/15/8/e249290.full
SO  - BMJ Case Reports2022 Aug 01; 15
AB  - A woman in her 60s with a history of adult-onset Still’s disease (AOSD) in remission for 14 years received the ChAdOx1-S vaccine as a booster to her initial vaccination schedule (two doses of CoronaVac vaccine 6 months apart). Two weeks later, she consulted for symptoms suggestive of AOSD reactivation. This was confirmed during hospitalisation, where renal and cardiac involvement were also observed. Despite using high-dose corticosteroids, troponin T and N-terminal pro hormone B-type natriuretic peptide (NT-proBNP) were persistently elevated. Tocilizumab was used, with which the patient achieved complete remission of her symptoms and normalised her laboratory tests.