@article {Chamberse248162, author = {Joshua Chambers and Alice Appleton and Christopher Dudley}, title = {Pancreatic insufficiency as a complication of type 1 diabetes causing enteric hyperoxaluria in a transplant kidney}, volume = {15}, number = {7}, elocation-id = {e248162}, year = {2022}, doi = {10.1136/bcr-2021-248162}, publisher = {BMJ Specialist Journals}, abstract = {A kidney transplant recipient with a medical history of type 1 diabetes mellitus (T1DM) presents to the clinic with an acute kidney injury (AKI) and diarrhoea. Kidney biopsy found deposition of focal oxalate crystals, and further investigation revealed a raised 24-hour urinary oxalate and reduced faecal elastase. Therefore, we present a case of acute oxalate nephropathy (AON) secondary to enteric hyperoxaluria as a result of pancreatic insufficiency caused by T1DM. T1DM is a common cause of end-stage renal failure and exocrine pancreatic insufficiency. Therefore, AON secondary to enteric hyperoxaluria should be considered in patients with a transplant AKI. Earlier testing of 24-hour urinary oxalate and faecal elastase could generate diagnosis before biopsy results and allow commencement of pancreatic replacement therapy earlier to avoid permanent loss of kidney function.}, URL = {https://casereports.bmj.com/content/15/7/e248162}, eprint = {https://casereports.bmj.com/content/15/7/e248162.full.pdf}, journal = {BMJ Case Reports CP} }