RT Journal Article
SR Electronic
T1 Autoimmune storm following alemtuzumab
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e248037
DO 10.1136/bcr-2021-248037
VO 15
IS 6
A1 Chelsea Chan
A1 Philippe Beauchemin
A1 Ana-Luiza Sayao
A1 Mollie Carruthers
YR 2022
UL http://casereports.bmj.com/content/15/6/e248037.abstract
AB Alemtuzumab has been associated with the emergence of secondary autoimmune diseases. We report a case of a patient with relapsing–remitting multiple sclerosis who developed a refractory immune thrombocytopaenia associated with vasculitis, myelofibrosis and later Guillain-Barré syndrome following alemtuzumab. The medical community should be aware of unusual and unexpected adverse events that may be associated with alemtuzumab, especially when occurring simultaneously in the same patient.