PT - JOURNAL ARTICLE AU - Taylor Becker AU - Matthew Smith AU - Meredith Parsons AU - Michihiko Goto TI - Non-tuberculous mycobacterial thoracic osteomyelitis in an immunocompetent host: a rare presentation of <em>Mycobacterium kansasii</em> AID - 10.1136/bcr-2022-249629 DP - 2022 May 01 TA - BMJ Case Reports PG - e249629 VI - 15 IP - 5 4099 - http://casereports.bmj.com/content/15/5/e249629.short 4100 - http://casereports.bmj.com/content/15/5/e249629.full SO - BMJ Case Reports2022 May 01; 15 AB - An immunocompetent man in his 40s presented with 3 months of mid-thoracic back pain which progressed to include progressive paraesthesias and lower extremity weakness. Investigations revealed thoracic spine osteomyelitis with signs of cord compression. He underwent neurosurgical intervention, including laminectomy, spinal cord decompression and partial resection of an epidural mass. Initial intraoperative biopsy and surgical pathology results were concerning for an acid-fast bacillus as the causative pathogen, and the patient was given empiric therapy for presumed Mycobacterium tuberculosis. However, microbiology speciation revealed the presence of the non-tuberculous mycobacterium (NTM) Mycobacterium kansasii, which resulted in an alteration of his antimicrobial therapy. This case highlights the importance of considering NTM as a possible aetiology of spinal osteomyelitis, even among immunocompetent individuals or in low-prevalence regions.