PT - JOURNAL ARTICLE AU - Ariadna de Genover Gil AU - Gabriel Manuel Gonzalez Suarez AU - Carla Moret Puig AU - Abelardo Hurtado Ganoza TI - Superwarfarin poisoning: challenges still remain AID - 10.1136/bcr-2021-248385 DP - 2022 May 01 TA - BMJ Case Reports PG - e248385 VI - 15 IP - 5 4099 - http://casereports.bmj.com/content/15/5/e248385.short 4100 - http://casereports.bmj.com/content/15/5/e248385.full SO - BMJ Case Reports2022 May 01; 15 AB - Superwarfarin (long-acting anticoagulant rodenticide) poisoning should be suspected in unexplained bleeding with prolonged prothrombin time, especially in the absence of another explanation. Diagnosis and treatment of this intoxication remain a challenge as the direct analysis of superwarfarin in serum is not always possible. Therefore, toxin bioavailability remains unknown and close monitoring and treatment for long periods are required to avoid serious bleeding complications. Here, we discuss a case of suspected superwarfarin poisoning to highlight the challenges in early diagnosis and the challenges we encountered in treatment management and ensuring compliance for long periods.