RT Journal Article SR Electronic T1 Neisseria gonorrhoeae infective endocarditis JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e249723 DO 10.1136/bcr-2022-249723 VO 15 IS 5 A1 Marylou Fenech A1 Thelma Xerri A1 Paula Grech A1 Anette Portelli YR 2022 UL http://casereports.bmj.com/content/15/5/e249723.abstract AB We present a case of endocarditis secondary to disseminated Neisseria gonorrhoeae infection affecting the native tricuspid valve. After a thorough workup, our patient was treated conservatively with appropriate intravenous antibiotic therapy for 6 weeks. A follow-up echocardiogram showed resolution of the vegetation without any residual valvular involvement. Literature review reveals 99 cases of infective endocarditis which occurred secondary to N. gonorrhoeae infection, of which, only 4 cases (6%) affected the tricuspid valve. Through this case report, we highlight the importance of thorough history taking including a sexual and social history, as well as careful recognition of the clinical signs, which helped us reach this uncommon diagnosis while always maintaining a high clinical suspicion of rare causes of endocarditis.