PT - JOURNAL ARTICLE AU - Marylou Fenech AU - Thelma Xerri AU - Paula Grech AU - Anette Portelli TI - <em>Neisseria gonorrhoeae</em> infective endocarditis AID - 10.1136/bcr-2022-249723 DP - 2022 May 01 TA - BMJ Case Reports PG - e249723 VI - 15 IP - 5 4099 - http://casereports.bmj.com/content/15/5/e249723.short 4100 - http://casereports.bmj.com/content/15/5/e249723.full SO - BMJ Case Reports2022 May 01; 15 AB - We present a case of endocarditis secondary to disseminated Neisseria gonorrhoeae infection affecting the native tricuspid valve. After a thorough workup, our patient was treated conservatively with appropriate intravenous antibiotic therapy for 6 weeks. A follow-up echocardiogram showed resolution of the vegetation without any residual valvular involvement. Literature review reveals 99 cases of infective endocarditis which occurred secondary to N. gonorrhoeae infection, of which, only 4 cases (6%) affected the tricuspid valve. Through this case report, we highlight the importance of thorough history taking including a sexual and social history, as well as careful recognition of the clinical signs, which helped us reach this uncommon diagnosis while always maintaining a high clinical suspicion of rare causes of endocarditis.