TY - JOUR T1 - A Low rectal GIST JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2021-248505 VL - 15 IS - 3 SP - e248505 AU - Tara M Connelly AU - Cillian Clancy AU - Shaomin Hu AU - Scott R Steele AU - Hermann Kessler Y1 - 2022/03/01 UR - http://casereports.bmj.com/content/15/3/e248505.abstract N2 - A man in his 70s presented with narrowing of his stool calibre and a palpable mass on rectal examination. Colonoscopy revealed a submucosal bulge without a mucosal lesion. CT and MRI demonstrated an 8×5.4×7 cm mass in lower rectum. Biopsy of the mass confirmed a rectal gastrointestinal stromal tumour (GIST). It was moderately sensitive to neoadjuvant imatinib and radiotherapy, which slightly downsized the tumour. He required abdominal perineal resection with curative intent. Uncommonly found in the rectum, when located here, GISTs are typically aggressive and are a rare cause of stool calibre narrowing. Rectal GISTs should be considered in patients presenting with this symptom. ER -