PT  - JOURNAL ARTICLE
AU  - Emilie Anderssen-Nordahl
AU  - Judit Riera-Arnau
AU  - Manel Perelló Carrascosa
AU  - Alicia Gómez Muñoz
TI  - Application of pharmacovigilance tools in a case of subacute anterior angle narrowing while under furosemide exposure
AID  - 10.1136/bcr-2021-244581
DP  - 2022 Jan 01
TA  - BMJ Case Reports
PG  - e244581
VI  - 15
IP  - 1
4099  - http://casereports.bmj.com/content/15/1/e244581.short
4100  - http://casereports.bmj.com/content/15/1/e244581.full
SO  - BMJ Case Reports2022 Jan 01; 15
AB  - Sulfonamides have been related to drug-induced acute angle closure of the eye, but scarce reports exist concerning furosemide. We describe the second case of acute chamber narrowing (ACN) during furosemide exposure. A 65-year-old man with a renal transplant presented with ACN, after 3 months of furosemide intake. Finally, the patient required a bilateral iridotomy and right lens replacement. ACN has been associated with drugs containing sulfonamide derivatives, but an evaluation with pharmacovigilance scales for adverse drug reaction (ADR)-standardised causality assessment has not been provided. We use this case to illustrate how medicines and an ADR should be evaluated and reported. The spreading of pharmacovigilance information on what should be a rare and unexpected condition related to a drug could mean that other reports emerge about ADR with this drug and regulatory agencies perform consequently, as happened with topiramate.