RT Journal Article SR Electronic T1 Bilateral, chronic, bacterial conjunctivitis in giant fornix syndrome JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e245460 DO 10.1136/bcr-2021-245460 VO 15 IS 1 A1 Patrick Commiskey A1 Eve Bowers A1 Aidan Dmitriev A1 Alex Mammen YR 2022 UL http://casereports.bmj.com/content/15/1/e245460.abstract AB Giant fornix syndrome (GFS) results in chronic, relapsing conjunctivitis in elderly patients with enophthalmos and enlarged fornices, in which infectious material collects and perpetuates inflammation. A 98-year-old woman presented with persistent, bilateral, purulent conjunctivitis; corneal epithelial defects and progressive blepharospasm that did not respond to artificial tears, topical antibiotics and steroids and amniotic membrane grafts. Additional findings of deep-set orbits with enlarged upper fornices were diagnostic of GFS. Over the next 2 months, she responded to a combination of topical and systemic antibiotics, autologous serum eye drops, povidone-iodine forniceal rinses, and hypochlorous acid treatment of the eyelashes. GFS is an important diagnostic consideration in elderly patients with chronic conjunctivitis and deep-set orbits.