PT - JOURNAL ARTICLE AU - Lindsey M Shain AU - Taha Ahmed AU - Michele L Bodine AU - Jennifer G Bauman TI - Drug use-related right-sided infective endocarditis complicated by empyema and bronchopleural fistula AID - 10.1136/bcr-2021-246663 DP - 2022 Jan 01 TA - BMJ Case Reports PG - e246663 VI - 15 IP - 1 4099 - http://casereports.bmj.com/content/15/1/e246663.short 4100 - http://casereports.bmj.com/content/15/1/e246663.full SO - BMJ Case Reports2022 Jan 01; 15 AB - Right-sided infective endocarditis is frequently accompanied by septic pulmonary emboli, which may result in a spectrum of respiratory complications. We present the case of a 25-year-old woman diagnosed with infective endocarditis secondary to intravenous drug use. During a long and arduous hospital course, the patient developed empyema with bronchopleural fistula, representing severe but uncommon sequelae that may arise from this disease process. She was treated with several weeks of antibiotics as well as surgical thorascopic decortication and parietal pleurectomy.