RT Journal Article
SR Electronic
T1 Eosinophilic fasciitis (Shulman disease) with clinical, imaging and pathological correlation
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e246151
DO 10.1136/bcr-2021-246151
VO 14
IS 12
A1 Primitivo, Ana
A1 Madeira, Nathalie
A1 Lopez, Dolores
A1 Afonso, Diana
YR 2021
UL http://casereports.bmj.com/content/14/12/e246151.abstract
AB Eosinophilic fasciitis (EF) is a rare subacute fibrosing disorder of unknown aetiology, characterised by thickening of the muscular fascia and subcutaneous tissue, leading to swelling of limbs and trunk and sparing fingers and toes. Eosinophilic infiltration and degranulation may prompt tissue damage and consequent fibrosis due to the accumulation of collagen and extracellular matrix proteins. MRI is the best imaging modality for diagnosis, depicting fascial thickening and enhancement. MRI may also have a significant role in excluding alternative diagnosis and guiding the skin–muscle biopsy.We report a case of EF with clinical and pathological correlation, highlighting the diagnostic value of MRI for early diagnosis and further treatment.