RT Journal Article SR Electronic T1 Graves’ disease following administration of second dose of SARS-CoV-2 vaccine JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e246432 DO 10.1136/bcr-2021-246432 VO 14 IS 12 A1 Timothy James Goblirsch A1 Ambika E Paulson A1 Gerti Tashko A1 Asefa Jejaw Mekonnen YR 2021 UL http://casereports.bmj.com/content/14/12/e246432.abstract AB The SARS-CoV-2 vaccines have had an overwhelming success in curbing the COVID-19 global pandemic, accounting for countless lives saved. Adverse reactions are inevitable, given the vast scale of vaccination required to mitigate future surges of COVID-19. Hyperthyroid disorders have been reported as potential adverse reactions to SARS-CoV-2 vaccines in two patients with Graves’ disease and a group of adults with subacute thyroiditis occurring in young women healthcare workers. We report a case of clinical Graves’ disease in a woman with a previously stable multinodular goitre that occurred 14 days following her second dose of Pfizer-BioNTech SARS-CoV-2 vaccine.