PT - JOURNAL ARTICLE AU - Timothy James Goblirsch AU - Ambika E Paulson AU - Gerti Tashko AU - Asefa Jejaw Mekonnen TI - Graves’ disease following administration of second dose of SARS-CoV-2 vaccine AID - 10.1136/bcr-2021-246432 DP - 2021 Dec 01 TA - BMJ Case Reports PG - e246432 VI - 14 IP - 12 4099 - http://casereports.bmj.com/content/14/12/e246432.short 4100 - http://casereports.bmj.com/content/14/12/e246432.full SO - BMJ Case Reports2021 Dec 01; 14 AB - The SARS-CoV-2 vaccines have had an overwhelming success in curbing the COVID-19 global pandemic, accounting for countless lives saved. Adverse reactions are inevitable, given the vast scale of vaccination required to mitigate future surges of COVID-19. Hyperthyroid disorders have been reported as potential adverse reactions to SARS-CoV-2 vaccines in two patients with Graves’ disease and a group of adults with subacute thyroiditis occurring in young women healthcare workers. We report a case of clinical Graves’ disease in a woman with a previously stable multinodular goitre that occurred 14 days following her second dose of Pfizer-BioNTech SARS-CoV-2 vaccine.