PT  - JOURNAL ARTICLE
AU  - Alexander Anderson
AU  - Mary Seddon
AU  - Khalid Shahzad
AU  - Raimundas Lunevicius
TI  - Post-COVID-19 vaccination occurrence of splenic infarction due to arterial thrombosis
AID  - 10.1136/bcr-2021-243846
DP  - 2021 Dec 01
TA  - BMJ Case Reports
PG  - e243846
VI  - 14
IP  - 12
4099  - http://casereports.bmj.com/content/14/12/e243846.short
4100  - http://casereports.bmj.com/content/14/12/e243846.full
SO  - BMJ Case Reports2021 Dec 01; 14
AB  - We present the case of an 82-year-old woman admitted to a regional emergency general surgery centre with severe left upper quadrant abdominal pain and tenderness within 21 days of receiving the first dose of the ChAdOx1 nCov-19 vaccine (Vaxzevria, AstraZeneca). Following further investigation through CT imaging, a thrombus was discovered in the patient’s splenic artery resulting in a large splenic infarct. Splenic infarcts are rare and it is important to note the association between time of administration of the first dose of vaccine and the occurrence of thromboembolic complications in the noted absence of other risk factors for this condition. We hypothesise a link between Vaxzevria vaccine injection and a rare form of thromboembolic complication: thrombosis of the splenic artery.