RT Journal Article SR Electronic T1 Primary synchronous malignancies of the breast and the kidney JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e243563 DO 10.1136/bcr-2021-243563 VO 14 IS 10 A1 Khan, Rehan Nasir A1 Kazmi, Zehra A1 Vohra, Lubna Mushtaque A1 Uddin, Zeeshan YR 2021 UL http://casereports.bmj.com/content/14/10/e243563.abstract AB Synchronous primary malignancies are most frequently seen with cancers of the stomach and oesophagus, mainly attributed to the similar genetic mutations. Most of these multiple malignancies turn out to be metastatic or metachronous lesions. Multiple synchronous malignancies are rarer than metachronous ones. Primary synchronous breast and renal cancer is even rare. These patients require extensive workup to exclude all possible metastases. The nature of the primary tumours must also be confirmed, prior to any treatment strategy. We report the case of a healthy, middle-aged woman who initially presented with a lesion suspicious for breast carcinoma, and further workup revealed the presence of an asymptomatic, synchronous primary renal cell cancer, which is a very rare presentation.