RT Journal Article SR Electronic T1 Sphenoid sinusitis: a rare cause of ischaemic stroke JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e242943 DO 10.1136/bcr-2021-242943 VO 14 IS 10 A1 Young, Kenneth Stuart A1 Kiam, Jian Shen A1 Metcalf, Kneale A1 Nassif, Ramez YR 2021 UL http://casereports.bmj.com/content/14/10/e242943.abstract AB We present the case of a 61-year-old woman who presented to the accident and emergency department with an ischaemic stroke, on a background of receiving intravenous and oral antibiotics to treat chronic left sphenoid sinusitis. Initially presenting with right-sided weakness and aphasia, a diagnosis of acute ischaemic stroke was made. Antibiotics had been commenced 1 month prior to the ischaemic stroke. Imaging at that time showed changes in keeping with chronic sphenoid sinusitis along with a small dehiscence in the lateral wall of the left sphenoid sinus and thrombosis of the left superior ophthalmic vein. During that admission blood cultures grew Streptococcus constellatus, a member of the Streptococcus milleri group. We discuss the unusual aetiology of this stroke, the emerging evidence associating chronic rhinosinusitis with stroke and the complex multidisciplinary approach required for management in this case.