TY - JOUR T1 - Hypereosinophilia: a rare cause of stroke and multiorgan dysfunction JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2021-242619 VL - 14 IS - 10 SP - e242619 AU - Kapil L Barbind AU - Revanth Boddu AU - KP Shijith AU - Kundan Mishra Y1 - 2021/10/01 UR - http://casereports.bmj.com/content/14/10/e242619.abstract N2 - Eosinophilia can occur due to a plethora of allergic, infective, neoplastic and idiopathic conditions. Hypereosinophilic syndrome (HES) is characterised by sustained eosinophilia and multiorgan dysfunction in the absence of an identifiable cause. It may range from a self-limiting condition to a rapidly progressive life-threatening disorder, of which ischaemic stroke is a rare presentation. Such episodes can rarely be the presenting manifestation, and may develop before any other laboratory abnormality or organ involvement. We report a case of HES presented with multiorgan (neurological and renal) involvement, managed successfully with steroids and cytoreductive therapy. High initial absolute eosinophil count can be a clue to the diagnosis and early treatment should be initiated in such patients, to prevent fatal outcomes. ER -