TY - JOUR T1 - Complex case of COVID-19 and infective endocarditis JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2021-242205 VL - 14 IS - 8 SP - e242205 AU - Katrin Alizadeh AU - Danielle Bucke AU - Sadia Khan Y1 - 2021/08/01 UR - http://casereports.bmj.com/content/14/8/e242205.abstract N2 - A 50-year-old man with no medical history of note presented with new onset of confusion and dyspnoea. He tested positive for coronavirus (COVID-19), and subsequently, was admitted to the intensive care unit due to severe sepsis and acute renal failure requiring haemodialysis. Shortly afterwards, he was intubated due to haemodynamic instability. His blood culture was positive for Staphylococcus aureus bacteraemia, and echocardiogram showed evidence of vegetation in the aortic valve area. He was commenced on intravenous antibiotics for infective endocarditis (IE). Following extubation, he underwent an MRI of the spine due to increasing back pain. This was suggestive of L5–S1 discitis, likely secondary to septic emboli from IE. A few days later, he developed acute ischaemia of the left toes and extensive thrombosis of the right cubital and left iliac veins. Following a prolonged hospital admission, he was discharged home and later underwent an elective forefoot amputation from which he made a good recovery. ER -