RT Journal Article
SR Electronic
T1 Isolated optic neuropathy due to folate deficiency with associated iron overload
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e242399
DO 10.1136/bcr-2021-242399
VO 14
IS 7
A1 Pique, Karina
A1 Taber, William
A1 Thompson, Anthony
A1 Maitland, Charles Gerry
YR 2021
UL http://casereports.bmj.com/content/14/7/e242399.abstract
AB Isolated optic neuropathy due to folate deficiency is rarely reported. Poor dietary practices, malabsorption, and tobacco/alcohol abuse are usually responsible. We examined a patient with blinding optic neuropathies and isolated folic acid deficiency. Visual acuity recovered after folate replacement. At the same time, serological investigation revealed high ferritin and iron saturation levels with negative genetic markers for haemochromatosis consistent with the diagnosis of iron overload syndrome. There are no reports of blindness associated with iron overload syndrome.