RT Journal Article
SR Electronic
T1 Malignant idiopathic intracranial hypertension revealed a hidden primary spinal leptomeningeal medulloblastoma
JF BMJ Case Reports
JO BMJ Case Reports
FD BMJ Publishing Group Ltd
SP e243506
DO 10.1136/bcr-2021-243506
VO 14
IS 7
A1 Naim Izet Kajtazi
A1 Shahpar Nahrir
A1 Wafa Al Shakweer
A1 Juman Al Ghamdi
A1 Ali Al Fakeeh
A1 Majed Al Hameed
YR 2021
UL http://casereports.bmj.com/content/14/7/e243506.abstract
AB Frequently the cause of raised intracranial pressure remains unresolved and rarely is related to spinal tumours, moreover less to spinal medulloblastoma without primary brain focus. An 18-year-old woman had a 3-month history of headache and impaired vision. Neurological examination revealed bilateral sixth cranial nerve palsies with bilateral papilloedema of grade III. No focal brain or spine lesion was found on imaging. Consecutive lumbar punctures showed high opening pressure and subsequent increasing protein level. Meningeal biopsy was negative. At one point, she developed an increasing headache, vomiting and back pain. Spine MRI showed diffuse nodular leptomeningeal enhancement with the largest nodule at T6–T7. Malignant cells were detected in cerebrospinal fluid. She underwent laminectomy with excisional biopsy, and pathology showed medulloblastoma WHO grade IV. She was treated with chemotherapy and craniospinal irradiation and made a good recovery.