TY - JOUR T1 - Acute encephalitis, myoclonus and Sweet syndrome after mRNA-1273 vaccine JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2021-243173 VL - 14 IS - 7 SP - e243173 AU - Gabriel Torrealba-Acosta AU - Jennifer C Martin AU - Yve Huttenbach AU - Catherine R Garcia AU - Muhammad R Sohail AU - Sandeep Krishna Agarwal AU - Carina Wasko AU - Eric M Bershad AU - Mohammad I Hirzallah Y1 - 2021/07/01 UR - http://casereports.bmj.com/content/14/7/e243173.abstract N2 - A patient presented with fever, generalised rash, confusion, orofacial movements and myoclonus after receiving the first dose of mRNA-1273 vaccine from Moderna. MRI was unremarkable while cerebrospinal fluid showed leucocytosis with lymphocyte predominance and hyperproteinorrachia. The skin evidenced red, non-scaly, oedematous papules coalescing into plaques with scattered non-follicular pustules. Skin biopsy was consistent with a neutrophilic dermatosis. The patient fulfilled the criteria for Sweet syndrome. A thorough evaluation ruled out alternative infectious, autoimmune or malignant aetiologies, and all manifestations resolved with glucocorticoids. While we cannot prove causality, there was a temporal correlation between the vaccination and the clinical findings. ER -