PT - JOURNAL ARTICLE AU - Hrishikesh Kaza AU - Jignesh Manshibhai Gala AU - Padmaja Kumari Rani TI - Subfoveal retinal pigment epithelium inflammatory lesion presenting as a sign of reactivation of tubercular multifocal choroiditis AID - 10.1136/bcr-2020-240280 DP - 2021 May 01 TA - BMJ Case Reports PG - e240280 VI - 14 IP - 5 4099 - http://casereports.bmj.com/content/14/5/e240280.short 4100 - http://casereports.bmj.com/content/14/5/e240280.full SO - BMJ Case Reports2021 May 01; 14 AB - Multifocal choroiditis (MFC) can be associated with ocular tuberculosis (TB). Inflammatory peripapillary choroidal neovascular membrane (PPCNVM) is uncommon in TB MFC. Subretinal pigment epithelial inflammatory lesions are suggestive of acute inflammation or reactivation of inflammation in the setting of MFC. We present a case of MFC, of tubercular aetiology, during course of treatment of PPCNVM developed a subfoveal retinal pigment epithelial lesion. Clinical examination suggested a recurrence of PPCNVM, with the new macular lesions posing a dilemma of new onset inflammatory choroidal neovascular membrane (CNVM) at the macula versus reactivation of choroiditis at the posterior pole. Multimodal imaging helped differentiate the lesion from CNVM and give the appropriate antitubercular treatment to prevent future recurrences.