TY - JOUR T1 - Vanishing lung syndrome: a consequence of mixed tobacco and marijuana use JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2020-239255 VL - 14 IS - 5 SP - e239255 AU - Jordan R Salley AU - Vishal Kukkar AU - Lanna Felde Y1 - 2021/05/01 UR - http://casereports.bmj.com/content/14/5/e239255.abstract N2 - Idiopathic giant bullous emphysema or vanishing lung syndrome (VLS) is a rare, chronic radiological diagnosis characterised by giant emphysematous bullae located primarily in the upper lobes of the lungs. This highly morbid phenotype of chronic obstructive pulmonary disease leads to severe progressive dyspnoea and significant disability. Here, we describe a 48-year-old man with a history significant for long-term tobacco and cannabis smoking, who is found to have VLS. We present a review of recent findings on the association between VLS and the additive effect of marijuana and tobacco. ER -