TY - JOUR T1 - COVID-19 triggering mucormycosis in a susceptible patient: a new phenomenon in the developing world? JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2021-241663 VL - 14 IS - 4 SP - e241663 AU - Shweta Mallikarjun Revannavar AU - Supriya P S AU - Laxminarayana Samaga AU - Vineeth V K Y1 - 2021/04/01 UR - http://casereports.bmj.com/content/14/4/e241663.abstract N2 - A middle-aged woman with diabetes presented with left-sided facial pain, complete ptosis and fever of short duration. On presentation, she had hyperglycaemia without ketosis. There was total ophthalmoplegia of the left eye with a visual acuity of 6/36. She incidentally tested positive for COVID-19. CT paranasal sinus and MRI brain revealed left-sided pansinusitis with acute infarct in the left parieto-occipital region without angioinvasion. An emergency functional endoscopic sinus procedure was done, which confirmed mucormycosis on histopathological examination. After 1 week of conventional amphotericin B and antibiotics, repeat CT brain showed improvement in mucosal thickening and sinusitis. This case is a rare presentation of mucormycosis associated with rapid progression to orbital apex syndrome with brain infarction in a patient with non-ketotic diabetes and COVID-19. Early diagnosis and treatment are essential to prevent further end-organ damage. It is also interesting that there was no angioinvasion and transient periarterial inflammation was attributed to brain infarction. ER -