TY - JOUR T1 - Hyperregenerative macrocytic anaemia: the role of copper and zinc JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2020-241028 VL - 14 IS - 4 SP - e241028 AU - Patrick Hofmann AU - Claudia Buetikofer AU - Esther Bächli Y1 - 2021/04/01 UR - http://casereports.bmj.com/content/14/4/e241028.abstract N2 - In a patient with a history of bariatric surgery, severe copper deficiency presenting with macrocytic hyperregenerative anaemia was diagnosed. Besides the impaired intestinal absorption due to a short bowel syndrome, the enteral zinc supplementation competitively decreased the intestinal copper uptake. Once the zinc supplementation was stopped, enteral copper replacement ensued and normalised haemoglobin levels with decreasing median corpuscular volume were observed during follow-up visits. ER -