PT - JOURNAL ARTICLE AU - GAP van Gorp AU - PJLT Sanders AU - DA van Waardenburg AU - Monique Engel TI - COVID-19 pneumonia successfully managed with high-flow nasal cannula in a 15-year-old boy AID - 10.1136/bcr-2020-239682 DP - 2021 Apr 01 TA - BMJ Case Reports PG - e239682 VI - 14 IP - 4 4099 - http://casereports.bmj.com/content/14/4/e239682.short 4100 - http://casereports.bmj.com/content/14/4/e239682.full SO - BMJ Case Reports2021 Apr 01; 14 AB - We report an otherwise healthy, fully immunised 15-year-old boy who was transferred to our Pediatric intensive care unit with 4 days of fever, dry cough, increased work of breathing and impending respiratory failure. Two days prior, amoxicillin/clavulanic acid was prescribed for lower airway symptoms resembling pneumonia. PCR of the nasopharyngeal swab revealed an active COVID-19 infection (Ct 19). The CT scan showed significant ground-glass opacities highly associated with COVID-19 (COVID-19 reporting and data system 4). Antibiotics were continued and chloroquine was given for 5 days. High-flow nasal cannula (HFNC) was started as respiratory support therapy with rapid decrease of tachypnoea and oxygen demand. HFNC was successfully stopped after 7 days. The patient made full clinical recovery. This case illustrates HFNC as a successful respiratory support therapy in a paediatric patient with an active COVID-19 pneumonia.