PT - JOURNAL ARTICLE AU - Michelle M de Leau AU - Remko S Kuipers TI - Cardiovascular complications of <em>Streptococcus pneumoniae</em> bacteraemia AID - 10.1136/bcr-2020-240341 DP - 2021 Apr 01 TA - BMJ Case Reports PG - e240341 VI - 14 IP - 4 4099 - http://casereports.bmj.com/content/14/4/e240341.short 4100 - http://casereports.bmj.com/content/14/4/e240341.full SO - BMJ Case Reports2021 Apr 01; 14 AB - The incidence of Streptococcus pneumoniae bacteraemia has risen due to a worldwide increase in immunocompromised patients and antibiotic resistance. We describe three patients who experienced severe, including cardiovascular, complications of pneumococcal bacteraemia. Cardiovascular complications related to pneumococci may run a fulminant course. However, some of these life-threatening complications (eg, endocarditis and aortitis) may long remain unnoticed or be misdiagnosed and therefore delay correct treatment. We review the literature with regards to the incidence, diagnosis and treatment of these rare but possibly lethal and hence important cardiovascular complications.