TY - JOUR T1 - Gorham-Stout disease: interesting cause of pleural effusion JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2020-239891 VL - 14 IS - 3 SP - e239891 AU - Daniel Olea-Mendoza AU - Vittorio Romeo Terrigno AU - Ayobamidele Balogun AU - Colleen Caprio Y1 - 2021/03/01 UR - http://casereports.bmj.com/content/14/3/e239891.abstract N2 - Gorham-Stout disease (GSD) is a rare disorder characterised by massive painless osteolysis due to lymphangiomatous tissue progression. GSD’s pathogenesis is still unclear, but osteoclasts' activation may play a role in its pathogenesis. There are multiple complications associated with GSD. One of the most severe and life-threatening complications is a chylothorax. Herein we discuss a case of a patient with a history of GSD who presented to the hospital with progressive dyspnoea secondary to a large left-sided pleural effusion, which was later confirmed to be a chylothorax. We will further discuss the current literature and treatment of chylothorax associated with GSD. ER -