TY - JOUR T1 - Hepatectomy for liver metastasis from rectal cancer in a patient with mitochondrial disease JF - BMJ Case Reports JO - BMJ Case Reports DO - 10.1136/bcr-2020-238653 VL - 14 IS - 2 SP - e238653 AU - Shogo Takei AU - Yuki Homma AU - Ryusei Matsuyama AU - Itaru Endo Y1 - 2021/02/01 UR - http://casereports.bmj.com/content/14/2/e238653.abstract N2 - We herein report a woman who was suffering from type 1 diabetes and hearing impairment and whose mother had mitochondrial disease. Abdominal ultrasound identified a hepatic tumour, and a further examination led to the diagnosis of rectal cancer with synchronous multiple liver metastases. A genetic test led to the diagnosis of mitochondrial disease with a mitochondrial gene 3243A>G mutation. After neoadjuvant chemotherapy, we performed hepatectomy and low anterior resection in one stage. Hepatic vascular exclusion was not performed in order to prevent damage to hepatocytes due to liver ischaemia, and Ringer’s lactate solution was not used to prevent lactic acidosis. The postoperative course was uneventful. Only one other case involving hepatectomy being performed in a patient with mitochondrial disease has been reported. Considering the extreme rarity of such cases and the importance of perioperative management, we report this case here. ER -